Weight Loss Pill That is Safe To Use Clinical Result Shows
Scientists are reporting what they say is the first clinical evidence of a drug successfully bringing about weight loss without putting the heart and cardiovascular system at risk.
"The study showed for the first time in a rigorous, randomised way that this weight loss drug helps people lose weight without causing an increase in adverse cardiovascular events in a population at higher risk for heart attacks and strokes,"
While Belviq was approved as a weight loss drug by the FDA back in 2012, data on its long-term safety was non-existent, which – in light of the kinds of health risks other anorectics have demonstrated – was a problem.
''Patients and their doctors have been nervous about using drugs to treat obesity, and for good reason,"
"There's a history of these drugs having serious complications."
To ascertain if lorcaserin posed the same kind of problems as its predecessors, Scientists ran a clinical test on 12,000 overweight or obese patients with a median age of 64 were randomly administered a twice-daily dose of the drug, or a placebo.
At the end of the trial – in which participants were monitored for a median period of 3.3 years – those who took the lorcaserin in addition to undergoing lifestyle interventions lost an average of 4 kilograms (9 lbs) on average, almost double the loss realised by those taking the placebo.
But we already knew lorcaserin, like other suppressants before it, successfully promoted (modest) weight loss – the more important finding here was that the drug did this sustainably, while not raising risk of cardiovascular events.
Over the duration of the study, 6.1 percent of the group taking lorcaserin experienced a major adverse cardiovascular event – effectively the same amount of people (6.2 percent) from the placebo group.
While nobody is suggesting lifestyle change shouldn't be the primary emphasis for most overweight and obese patients, a safe weight-loss drug like this could provide a much-needed third option in between diet/exercise adjustments and invasive surgical interventions such as bariatric tummy tucks.
this is a holy grail and one which has been certainly at the back of the mind of a lot of specialists for a long time."
It's worth bearing in mind that some participants taking the drug during the trial experienced adverse side effects, including dizziness, fatigue, headache, nausea, and diarrhoea.
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